This report summarizes activities on the French research vessel Pourquoi Pas? operating as part of the Office of Naval Research CALYPSO project during its main 2022 field program in the northwest Mediterranean. Other components of this field program included the Netherland’s research vessel R.V. Pelagia, a fleet of underwater gliders operated by the Scripps Oceanographic Institute and the Balearic Islands Coastal Observing and Forecasting System (SOCIB).